I use SuperDuper, and occasionally Carbon Copy Cloner to create weekly bootable backups of my Macs - except the wife's Macbook which lacks the essential Firewire port, but a full backup nevertherless. I aso use QRecall on all machines to create incremental backups at intervals of about 3 hours.
QRecall is a much understated application that does everything Time Machine does only a lot better. I have lost count of the number of Time machine backups that have been irretrievably corrupted, and while any backup can get damaged QRecall has built in tools to put things right and it tells you what it has done. The latest beta is faster than the production version but also rock solid, and the developer is very good at responding swiftly to questions and problems.
One of the main advantages of QRecall over Time machine is that the incremental backups are done at a block level so it copes quite happily with things like large database files only saving those bits that have changed.
Oh, I also use Crashplan for an online backup of my important data.
Belt n braces is my motto.
**"Consturbata sunt visera mea"**
Edited by Adrian (Tue 08-Mar-11 18:50:20)