Bought a new Samsung 840 250GB SSD for my 2010 MBP (5,4). Inserted the drive into a usb caddy, formatted it to "Mac OS Extended (Journaled)" then used Carbon Copy Cloner to clone my current HDD to the SSD.
Rebooted the MBP with the SSD still in the USB caddy, held option key down and selected the USB drive. This booted into OSX and all looked good and was working as expected.
Shutdown the MBP, removed the old HDD and installed the SSD into its place, started up the mac - not booting, can't select the drive, just get a folder icon with a question mark.
Reset NVRAM/PRAM and SMC - still no joy
Reinstalled the old HDD - that boots fine. SSD in the USB caddy boots fine again as well...
Anyone have an idea on what could be the cause of this issue? Is it a case of my MBP wont support a SSD?