There's also a school of thought with heating, and one I'll definitely look into if I need to do any work on mine, that you remove zone valves, TRVs (anything that impedes flow), run a flow temperature as low as possible so you get maximum condensing, and modulate the flame according to an outdoor temperature sensor and the knowledge of the actual heat loss of your property, rather than having a thermostat turn the boiler on full blast as soon as the indoor air dips below a certain level.
Most modern smart thermostats use OpenTherm (or <insert boiler proprietory control>) so the boiler modulates anyway. I wouldn't recommend removing TRVs, thermostats, etc, the problem with this is that regardless of the mathematics of the properties heat loss, different people will have different desired temperatures in different rooms, so you still need some sort of control.
It is still more economical having the boiler on full blast to heat your house up to temp, say, 30 mins before you get home, as opposed to leaving it on "low" for 8 hours during the day when you are not there.
A heat pump arrangement would be different of course, but I presume we're talking about Oil and Gas boilers here.
Andrews & Arnold Home ::1 on Draytek 2862ac - Why settle for inferior?