is this due to the 16qam?
Assuming you've checked the Operation Configuration U/S max data rate in RouterStatus is >20mbps then the capacity of each 16Qam channel will be about 18mbps (net or gross 4bits x 5120 ksym/s = 20.48mbps) shared by all CableModems on your cablesegment on that channel.
That's 2/3rds of (27mbps net) you get on 64Qam (6bits x 5120 etc....) that would typically be provisioned on an ArrisE6k CCAP/CMTS upgrade.
So quite possibly there is a U/S utilisation issue pending Arris upgrade or further noise busting to reliably allow 64QAM with Cisco 10k's in the interim?.