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It's fairly clear that the system has been compromised, even though you no longer see signs of it. Systems don't fix themselves, and few anti-malware products are so good that they can return a system to pristine condition without user intervention. Malware, on the other hand, can be very good at hiding itself.
I would be extremely suspicious of this system and work on the basis that, although it is now not evident, it is compromised. Who knows what key-loggers, remote-control applications, or Spam factories could be hidden on it. It should either be thoroughly cleaned or, better IMO, wiped and the OS re-installed.
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